Cytotoxic Activity of Ethyl Acetate Fraction Of Ethanolic Extract Green Algae (Ulva LACTUCA Linn.) On Mcf-7 Cells

Asriani Safitri, Eka and Nada Septiawan, Azizah and Pratiwi, Dinda and Emelda, Emelda (2019) Cytotoxic Activity of Ethyl Acetate Fraction Of Ethanolic Extract Green Algae (Ulva LACTUCA Linn.) On Mcf-7 Cells. In: THE FIRST ASIA – PASIFIC PARTNERSHIP ON HEALTH AND NUTRITION IMPROVEMENT (APHNI) CONFERENCE, 3 OKTOBER 2019, YOGYAKARTA.

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Abstract

Background: Based on data from the GLOBOCAN International Agency for Research on Cancer (IARC), in 2012 there were ± 14 million new cases of cancer and ± 8 million deaths from cancer worldwide. Various treatments were taken to overcome this type of cancer. On of the treatment for breast cancer is herbal medicine. The herbal medicine that are currently being discussed are plants that come from the sea (marine biota), one of which is green algae (Ulva lactuca Linn.). It is not yet known whether the ethanolic extract form and extract fraction also has antioxidant and cytotoxic abilities. Objectives: Conducted a cytotoxic test of the ethyl acetate fraction of green algae extract (Ulva lactuca Linn.) Methods: The method used is MTT Assay Results: IC50 value of Ethyl acetate fraction of ethanolic Extracts of Green Algae is1489,3 µg/ml and Ascorbic acid is 13,99 µg/ml Conclusions: The Ethyl Acetate Fraction of Green Algae Extract (Ulva lactuca Linn.) Have an IC50 value greater than the standard (Doxorubicin). Keywords: Green Algae, Cytotoxic Test, MTT Assay

Item Type: Conference or Workshop Item (Paper)
Additional Information: Publisher: Faculty of Health Sciences Alma Ata University Jl. Brawijaya 99, Yogyakarta 55183 Telp : (+62274) 434 2288,(0274) 434 2270 Email : uaa@almaata.ac.id ISBN: 978-623-223-055-2
Subjects: ILMU ILMU KESEHATAN > FARMASI
Divisions: FAKULTAS ILMU-ILMU KESEHATAN > S1 FARMASI
Depositing User: Awan Megantoro AMd
Date Deposited: 19 Aug 2020 04:20
Last Modified: 19 Aug 2020 04:20
URI: http://elibrary.almaata.ac.id/id/eprint/1921

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