COMPARISON OF REDUCTION FASTING BLOOD GLUCOSE (GDP) BY GIVING AMORPHOPHALLUS ONCHOPHYLLUS AND STROBILANTHES CRISPA ON TYPE 2 WISTAR RAT (RATTUS NOVERGICUS) INDUCED BY STREPTOZOTOSIN

RUKMAWATI, MITA and HADI, HAMAM and NURINDA, EVA and EMELDA, EMELDA and FAUZI, RIZAL and ESTININGSIH, DARU and KURNIASARI, YULINDA and APRILIA, VERIANI (2019) COMPARISON OF REDUCTION FASTING BLOOD GLUCOSE (GDP) BY GIVING AMORPHOPHALLUS ONCHOPHYLLUS AND STROBILANTHES CRISPA ON TYPE 2 WISTAR RAT (RATTUS NOVERGICUS) INDUCED BY STREPTOZOTOSIN. In: THE FIRST ASIA – PASIFIC PARTNERSHIP ON HEALTH AND NUTRITION IMPROVEMENT (APHNI) CONFERENCE, 3 Oktober 2019, YOGYAKARTA.

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Abstract

Background: From the Riskesdas data in 2018, the number of people with diabetes mellitus increased to 8.5% from 6.9% in 2013. In its handling there were four pillars, namely education, physical activity, pharmacology and diet or food regulation, but the approach that was available to the community namely pharmacology and diet. In addition to setting schedules and quantities, choosing food types also determines changes in blood glucose levels. One of the plant types that have benefits for reducing blood glucose levels are porang flour and vile leaves. Objectives: To determine the differences of reduction in fasting blood glucose levels (GDP) in type 2 DM wistar rats (rattus novergicus) by administering porang flour (amorphophallus onchophyllus) and keji beling leaf extract (strobilanthes crispa). Methods: This study was an experimental pre-post test control group design approach. The number of samples was 36 male wistar rats which were divided into 6 treatment groups. Data were analyzed by Paired T-test with a significant degree of p-value <0.05. Results: Dose porang flour 0.5g / 200gBB reduced blood glucose levels 102.47 mg /dL in rat, dose 0.75g/200gBB reduced blood glucose levels 124.54mg/dL, dose 1g/200gBB reduced blood glucose levels 144.27mg/dL and keji beling leaf extract dose 0.3g/200gBB reduce blood glucose level 140.08mg/dL. Conclusion: There were significant differences in reduction fasting blood glucose levels in type 2 DM male wistar rats of in porang flour doses of 0.5g/200gBB and 0.75g/200gBB. Statistically, the porang flour dose of 1g/200gBB was not significantly different from the keji beling leaf extract 0.3g/200gBB. Keywords: Porang Flour, Keji Beling, Fasting Blood Glucose

Item Type: Conference or Workshop Item (Paper)
Additional Information: ISBN: 978-623-223-055-2
Subjects: ILMU ILMU KESEHATAN > ILMU GIZI
ILMU ILMU KESEHATAN > FARMASI
Divisions: FAKULTAS ILMU-ILMU KESEHATAN > PRODI S1 ILMU GIZI
Depositing User: Dian Nugroho Prasetyo. SIP. M.IP
Date Deposited: 10 Aug 2020 04:23
Last Modified: 09 Mar 2021 06:35
URI: http://elibrary.almaata.ac.id/id/eprint/1851

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